How To Find Out If Your A Bone Marrow Match

Becoming a Bone Marrow Donor at UCLA

Most healthy individuals age eighteen to 44 could be potential blood and marrow stem cell donors. For some people, finding the right donor for a bone marrow transplant may exist their just promise for a cure. UCLA Wellness helps bone marrow transplant recipients, their families and donors understand the procedure and the risks – and find the right match.

The National Marrow Donor Program runs a bone marrow registry. Potential donors tin join, exist tested and add their names to list of people willing to donate bone marrow to anyone in need. Whether you lot desire to become function of the os marrow registry or donate to a relative, the donation process is the same.

How to donate os marrow

For a bone marrow transplant to exist successful, the donor and the recipient take to be well matched. Unlike matching blood types, matching bone marrow stem cells is a flake more complicated.

To see if you are a potential bone marrow match, you will exist tested to notice out what type of human being leukocyte antigen (HLA) you lot have. HLA is a protein institute on nearly cells in your trunk — including those in your allowed arrangement. The closer the HLA match, the better chance that a bone marrow transplant volition succeed. Bone marrow produces the infection-fighting white blood cells that are cardinal to a functioning immune system.

The good news is that you don't accept to really donate bone marrow to find out if you're a match. The process starts with a simple cheek swab to provide a sample of your DNA. If you lot are a basic match for a recipient based on that examination, you'll have additional blood tests or cheek swabs. Those results will give doctors more details most your HLA type.

If you would similar to be tested as a lucifer for a relative who is existence treated at UCLA Health'south Claret and Bone Marrow Transplant & Cellular Therapies Plan, contact u.s.a.. The patient's doctor volition arrange all of your testing and respond any questions yous take nigh becoming a donor. Discover out more about how a recipient prepares for os marrow transplant.

Bone marrow donation process

If you are a friction match for someone needing a transplant, you will beginning the process of donating os marrow stem cells. This process is the same whether you are altruistic for a relative or for someone using the National Marrow Donor Program registry.

Earlier your donation, you volition spend a couple of days undergoing a consultation that includes:

Thorough wellness evaluation
Medical history
Claret tests
Filling out consent forms
Meeting with doctors nigh the donation procedure

How stem cells are extracted

There are two means to obtain the stem cells used in a bone marrow transplant. The transplant recipient'due south medico will determine which method is best for his or her condition. The ii procedures are:

Os marrow harvesting: Doctors utilise needles to withdraw liquid bone marrow from both sides of the dorsum of your pelvic bones. This is a surgical procedure that usually takes ane 60 minutes. You will receive anesthesia and then that you feel no pain during the extraction. Nigh people go abode from the hospital that same twenty-four hours, simply some donors stay overnight for observation.
Apheresis: Apheresis is a nonsurgical, outpatient procedure. Instead of collecting bone marrow, information technology allows for collection of peripheral blood stalk cells.

Grooming: For five days before apheresis, you will become injections of filgrastim. This drug stimulates your bone marrow to make more than stem cells and release them into your bloodstream.
Procedure: On the day of the donation, expect to spend upwards to viii hours at the collection facility. A catheter (thin, flexible tube) is placed in a large vein in your arm. The claret will period into a machine that separates the stalk cells from the blood. A catheter in your other arm transfers the remaining blood back to your body.

Bone marrow donation recovery

Equally you lot prepare to donate, you may exist worried well-nigh possible bone marrow donation risks. The vast bulk of donors feel few side effects — well-nigh of which are mild. Most donors report feeling completely recovered inside a few weeks of their donation.

The side effects will vary depending on the type of donation procedure yous had:

Side furnishings of os marrow harvesting:

The almost common side effects of bone marrow harvesting are related to anesthesia. If you accept general anesthesia, you may experience nausea or airsickness. If you take regional anesthesia (such as an epidural), you may have headaches or a decrease in blood pressure. There is a very small risk of having damage to os, fretfulness or muscles in the pelvis during the extraction process.

Side effects of apheresis:

Common side effects from the filgrastim injections include headache, bone or muscle aches, nausea, fatigue and indisposition. These typically diminish apace after you end taking the medication. During the donation process, you may have chills, tingling effectually the oral fissure, fingers and toes and muscle cramps. Your care squad can slow downwards the procedure to aid reduce these symptoms.

Joining the national bone marrow registry

The registry needs donors of all races and ethnicities to provide the best matches for the almost patients. They have donors between the ages of 18 and 60. Just because bone marrow transplant is virtually successful with younger donors, people ages 18 to 44 are preferred.

Donors must be in first-class wellness. Certain diseases, medications, treatments and weight limits can exclude you from becoming a donor.

For more than details nigh medical qualifications and how to donate bone marrow, go to Be The Friction match.

Contact us

If you are interested in donating bone marrow to a relative in our intendance, please contact our Adult Blood and Bone Marrow Transplant & Cellular Therapies Program at 310-206-6909.

Source: https://www.uclahealth.org/transplants/bmt/becoming-a-bone-marrow-donor#:~:text=To%20see%20if%20you%20are,bone%20marrow%20transplant%20will%20succeed.

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